May 23, 2023 3-5PM ET
Tuesday on The Robert Scott Bell Show:
Trial of Gates-Funded Vaccine Patch for Infants ‘Successful,’ Company Says An Atlanta-based biotech company last week said it successfully concluded the first-ever clinical trial testing of a microarray injection-free vaccine on children as young as 9 months old. Micron Biomedical tested microneedle-based delivery of the measles-rubella (MR) vaccine on children in Gambia with backing from the Bill & Melinda Gates Foundation and the Centers for Disease Control and Prevention (CDC). Microarray injections are administered via a microneedle patch that looks like a Band-Aid and is applied by pressing it to the skin. Once applied, microneedles penetrate the upper layer of the skin to deliver the vaccine. The study, which researchers presented last week at the Microneedles 2023 conference in Seattle, evaluated the safety, immunogenicity and acceptability of the leading commercially available MR vaccine from the Serum Institute of India delivered by Micron’s microarray technology in adults, toddlers and infants. Proponents of this vaccination method, such as Gavi, the Vaccine Alliance — of which the Gates Foundation is a founding member — call the patches “the future of vaccination, where these lifesaving interventions are delivered painlessly, without the need for syringes or perhaps even trained medical professionals.” “Supporting innovations in vaccine delivery is critical to addressing ongoing health inequities,” James Goodson, co-investigator for the study and senior scientist and epidemiologist at the CDC’s Global Immunization Division, said in the press release.
Special Guest – Leslie Manookian
Leslie Manookian, MBA, M.L.C. Hom is president and founder of Health Freedom Defense Fund. She is a former successful Wall Street business executive. Her career in finance took her from New York to London with Goldman Sachs. She later became Director of Alliance Capital in London running their European Growth Portfolio Management and Research businesses.
Leslie is also an award-winning documentary filmmaker. In 2011 she released The Greater Good to rave reviews and awards; a documentary she wrote and produced, which explores the debate surrounding vaccines. This impactful film brings increased awareness to this issue and the importance of health freedom.
Protecting Americans medical and health freedoms inspired Leslie to found Health Freedom Defense Fund. After observing the trampling of our constitutionally protected, inalienable rights for the past two decades, she was filled with trepidation as 2020 unfolded, aware of various pieces of legislation in place which would facilitate further erosion of the rights of Americans. HFDF was the result.
Leslie’s and HFDF’s mission rests on the foundational principle that bodily autonomy is the most sacred and precious of human rights and must be fervently guarded. Leslie and HFDF endeavor each and every day to instill that notion in the public consciousness and codify it in law.
The Race to Save the World from the Common Cold The Pharmaceutical Industry trumpeted another breakthrough as the FDA recently approved the world’s first vaccine for Respiratory Syncytial Virus (RSV), a common respiratory illness that usually causes mild, cold-like symptoms. According to the CDC those at greatest risk from RSV are: Premature infants; Infants, especially those 6 months and younger; Children younger than 2 years old with chronic lung disease or congenital (present from birth) heart disease; Children with weakened immune systems; Children who have neuromuscular disorders, including those who have difficulty swallowing or clearing mucus secretions. While noting that, “All but the youngest of children have had RSV multiple times, but few of us would know with any certainty that this bad cold was caused by that bad virus”, Pharma soldiered on with its mission to rid the world of this scarcely problematic condition. This RSV vaccine “first”, trade name AREXVY, is produced by Glaxo-Smith Kline, a company which holds the distinction for the largest health care fraud settlement in U.S. history. The rollout is planned for Fall of 2024 with the shots marketed for individuals 60 years of age and older. While the injections are being sold as protection for older adults this alleged disease has historically been noted for primarily attacking young children.
Bishop Unified School District to Pay $400,000 and Conduct Training for All Employees in Settlement Agreement for Harming Students During COVID-19 Pandemic With the help of retired U.S. Federal Judge Stephen G. Larson, Bishop Unified School District (BUSD) and a group of Parents who filed claims for damages for violation of their children’s civil rights finalized a settlement on April 27, 2023. Not only is the school district required to pay $400,000 because of the harm suffered by the children, BUSD must also provide counseling and tutoring for the students, and training for all BUSD faculty and staff on “public health, response to public health emergencies, informed consent, and bullying/harassment/retaliation issues.” Armed with vital information on Emergency Use Authorization (EUA) and informed consent laws from Health Freedom Defense Fund (HFDF) and its founder, Leslie Manookian, Bishop parents and residents began expressing concerns about BUSD’s handling of the COVID-19 pandemic at its August 2021 school board meeting. They urged BUSD to follow Title 21 U.S.C., the federal law for the use of EUA products, such as COVID-19 masks, testing, and vaccines. This law requires voluntary informed consent and the option to accept or refuse EUA products. The Parents also sought protection for students’ civil liberties and pleaded with board members to consider the negative outcomes of potentially punitive enforcement of what was merely state health guidance. BUSD instead implemented a medically nonsensical policy of handling school-based exposures, discriminatory COVID-19 testing based on vaccination status, and illegally excluding students from extracurriculars and sports.
If bird flu starts to spread among people, existing vaccines may be inadequate, experts say Wild birds and poultry flocks alike continue to drop dead from the highly pathogenic bird flu that began spreading globally in 2020. Almost 59 million commercial birds have already been culled in the United States. It’s the broadest outbreak of this type of avian flu, known as H5N1, since it was first identified in China in 1996. The virus’s proliferation and high fatality rate have prompted questions about two types of possible vaccines: those for birds and those for humans. H5N1 kills almost all the birds it infects; among reported cases in people since 2003, the death rate has been 56%. The U.S. Agriculture Department announced in April that it had started testing several vaccine candidates for poultry. Vaccines for people, meanwhile, would only be considered if the virus eventually undergoes a complicated string of mutations that allow it to spread from person to person. There’s no evidence of that yet. The U.S. recorded its only human case of H5N1 last April — the person was involved in culling poultry with presumed infections in Colorado. The United Kingdom reported two cases Tuesday, both poultry workers with asymptomatic infections detected via routine testing. Chile reported one infection in March and Ecuador one case in January. But scientists have long considered H5N1 to have pandemic potential. The U.S. has a stockpile of H5N1 flu shots in case such a crisis arises, but three experts said it would likely prove insufficient should this particular type of avian flu start infecting people. The shots have only been administered in trials and were derived from strains that circulated in 2004 and 2005.
Paper Money Diehards Refuse to Fold There’s another revolt brewing in the English heartlands. “Let’s boycott the shops that won’t take cash—where are they?” Debbie Hicks yelled into a microphone in the town square on a recent Saturday. A few in the 200-strong crowd murmured some names—a coffee shop, a bakery. “OK, we can do this,” Hicks said. “It’s not too late!” Some 200 years after textile workers smashed newfangled looms here during the first stirrings of the industrial revolution, other rebels are worried about a newer technology: tap-and-go bank cards and smartphone payment apps. Actual cash changes hands in only around 15% of transactions in the U.K., pushed out by the speed and convenience of using a card or phone. In parts of London, cash has become something akin to a prison currency like ramen noodles or cigarettes, circulated among panhandlers or those on the margins of society. An unlikely coalition warns that by giving up cash, people could be losing more than they bargained for. Bank-note printers have pooled resources to fund academic studies to demonstrate how cash is an important piece of infrastructure. Simon Youel at Positive Money, a London nonprofit focusing on financial inclusion, says cash is inherently democratic. By going card-only, bars and restaurants are trying to pull in what they see as the right kind of customer, usually younger and more affluent, he said. “They’re sending a signal about who’s welcome and who’s not.”
Special Guest Boyd Haley
Dr. Haley received his BS in Chemistry/Physics from Franklin College of Indiana in 1963. From 1964 to 66 he served as a medic in the U.S. Army. He obtained his M.S. in Chemistry at the University of Idaho (1967) and his Ph.D. in Chemistry/Biochemistry at Washington State University (1971). He was an NIH Postdoctoral Scholar in the Department of Physiology, Yale University Medical School from 1971 to 1974. His first academic appointment was at the University of Wyoming in 1974 where he was promoted to full professor in 1983. In 1985 he was hired by the University of Kentucky Markey Cancer Center with academic appointments as professor in the College of Pharmacy in the Division of Medicinal Chemistry and in the Department of Biochemistry. He was appointed to be Chair and Professor of Chemistry/Biochemistry in the Department of Chemistry from 1996 to 2005. Dr. Haley had funding from NIH from 1974 through 2007 to develop numerous componds useful for diagnostics involving photoaffinity labeling. He retired from the University of Kentucky in July 2008. He has lectured throughout the world and testified before Congressional committees and the Institute of Medicine regarding various aspects of mercury toxicity and neurological diseases.
Dr. Haley gave a seminar at a DAN (Defeat Autism Now) conference in 1999 and subsequently testified before Congress and two National Academy of Sciences Institute of Medicine Committee meetings in 2000 and 2004 regarding his hypothesis that thimerosal (the mercury containing vaccine preservative) was a likely factor in the exacerbation of the apparent autism increase in 1990s. Recently he has addressed the fact that oxidative stress is a common occurrence in many diseases and has addressed the associated, low glutathione levels in people with oxidative stress as a major risk factor for many viral infections including influenza, HIV and COVID19 infections.
To medically address the issue of oxidative stress Dr. Haley formed EmeraMed a small drug development company dedicated to developing a hydrophobic, non-toxic drug, emeramide, which has both exceptionally tight toxic metal chelation properties and hydroxyl free radical elimination properties. These properties make emeramide a very good treatment for several illnesses that have oxidative stress as a symptom. The chemical properties of emeramide make it capable of crossing all biomembranes allowing it to enter the cytoplasm of all cells of all tissues and allows it to cross the blood brain barrier to chelate toxic metals in central nervous system tissues. EmeraMed has filed the drug emeramide with the USA FDA an IND (investigational new drug) application and is now finishing the final FDA recommended and required studies to be able to submit a NDA (new drug application) in 2020 for its orphan drug designation for mercury toxicity.
Reversal of genetic brain iron accumulation by N,N’-bis(2-mercaptoethyl)isophthalamide, a lipophilic metal chelator, in mice N,N’-bis(2-mercaptoethyl)isophthalamide (NBMI) is a novel lipophilic metal chelator and antioxidant used in mercury poisoning. Recent studies have suggested that NBMI may also bind to other metals such as lead and iron. Since NBMI can enter the brain, we evaluated if NBMI removes excess iron from the iron-loaded brain and ameliorates iron-induced oxidative stress. First, NBMI exhibited preferential binding to ferrous (Fe2+) iron with a negligible binding affinity to ferric (Fe3+) iron, indicating a selective chelation of labile iron. Second, NBMI protected SH-SY5Y human neuroblastoma cells from the cytotoxic effects of high iron. NBMI also decreased cellular labile iron and lessened the production of iron-induced reactive oxygen species in these cells. Deferiprone (DFP), a commonly used oral iron chelator, failed to prevent iron-induced cytotoxicity or labile iron accumulation. Next, we validated the efficacy of NBMI in Hfe H67D mutant mice, a mouse model of brain iron accumulation (BIA). Oral gavage of NBMI for 6 weeks decreased iron accumulation in the brain as well as liver, whereas DFP showed iron chelation only in the liver, but not in the brain. Notably, depletion of brain copper and anemia were observed in BIA mice treated with DFP, but not with NBMI, suggesting a superior safety profile of NBMI over DFP for long-term use. Collectively, our study demonstrates that NBMI provides a neuroprotective effect against BIA and has therapeutic potential for neurodegenerative diseases associated with BIA.
N,N’bis-(2-mercaptoethyl) isophthalamide (NBMI) exerts neuroprotection against lead-induced toxicity in U-87 MG cells N,N’-bis(2-mercaptoethyl)isophthalamide (NBMI) is a novel lipophilic heavy metal chelator and thiol redox antioxidant. This study was designed to investigate the neuroprotective activity of NBMI in U-87 MG cells exposed to lead acetate (PbAc). Cells were pretreated with NBMI for 24 h prior to a 48 h exposure to PbAc. Cell death (55%, p < 0.0001) and reduction of intracellular GSH levels (0.70-fold, p < 0.005) induced by 250 µM Pb were successfully attenuated by NBMI pretreatment at concentrations as low as 10 µM. A similar pretreatment with the FDA-approved Pb chelator dimercaptosuccinic acid (DMSA) proved ineffective, indicating a superior PKPD profile for NBMI. Pretreatment with NBMI successfully counteracted Pb-induced neuroinflammation by reducing IL-1β (0.59-fold, p < 0.05) and GFAP expression levels. NBMI alone was also found to significantly increase ferroportin expression (1.97-fold, p < 0.05) thereby enhancing cellular ability to efflux heavy metals. While no response was observed on the apoptotic pathway, this study demonstrated for the first time that necrotic cell death induced by Pb in U-87 MG cells is successfully attenuated by NBMI. Collectively these data demonstrate NBMI to be a promising neuroprotective compound in the realm of Pb poisoning.
What Would We Do Without the FDA and EPA? What would actually happen if EPA and FDA died tomorrow? Would snake oil suddenly dominate the market? Would unscrupulous business produce harmful products? And would the rivers suddenly run with poison? Would East Palestine, Ohio happen all over the country? My first response is this: if bad things happened, at least they wouldn’t be legitimized by government officials. At least bureaucrats, at taxpayer expense, wouldn’t blanket the lapdog media with press releases pooh-poohing folks who dare to questions official narratives. At least if something bad happened, it would have to stand on its own, defend itself, and not have government skirts to hide under. That new situation alone would infuse would-be bad folks with renewed sobriety. “You mean I can’t call up a regulatory agency peopled with my buddies and get cover? Oh no, I’d better watch my step.” Bad things will always happen, but goodness, folks, we don’t need to finance and encourage them from government cronies; let’s eliminate the bad guys from the taxpayer payroll. Second, a sudden surge in interest from each of us would stimulate discussions and watchfulness knowing that the future is in our hands, not the government’s. Again, that sounds like la-la land, but when people realize they’re responsible for their situation, they always take interest and get involved. One of the reasons Americans are lackadaisical toward just about everything is because we’ve been lulled into the lie that the government should and can take care of us. It can’t and won’t. Third, if taxes to pay for all these agencies’ shenanigans were decreased so we the people could keep more of our money, we’d be able to finance all sorts of private watchdogs. Nonprofits like Robert F. Kennedy’s original Waterkeepers and Children’s Defense Fund would take on the big guys and all of us would be able to fund them better. Imagine a Wild West Watchdog culture—how about that?
Question of The Day!
Our household is greatly saddened by the loss of Dr. Buttar, a warrior in his own right. He’s helped us and inspired us without ever meeting us; our prayers go out to his family and friends.
I do have a question for you: my sweetie has had a plugged right ear for 9 days; it just won’t clear anymore (it did for the first 2 days). He depends on his super sensitive hearing in his work and as a really good recreational musician – he plays music by ear, but this has been impeded with the pressure dulling his ability to hear details.
His ear canal is clear. He’s tried some homeopathics (belladona, apis mel, pulsatilla, ?) and is now trying Benadryl (ugh! he’s desperate!) to see if it’s allergies. He doesn’t normally have allergies, but with the heavy rains in CA, there might be more of everything in the air right now. Any ideas?
We are so thankful for your crusade for health empowerment – please keep up the great work!